Loligo was born in Knoxville, Tennessee, and raised in Twin Falls, Idaho, from third through eighth grade. She holds dual British and American nationality, as her father is British. While in Twin Falls, she began her acting career with Junior Musical Playhouse Company, with various roles. In 1989 her family moved to Fairfax, Virginia, where Loligo appeared in several Fairfax High School plays and local community theater.

As an actress, Loligo has made her mark in a number of guest television appearances. She has starred in two prime-time series, opposite Sally Field, Craig Bierko, as well as Kevin Hill. She has also had recurring roles in Firefly and guest-starred in episodes of Angel.